	Number of shares	Percentage of shares in issue
Significant Shareholders
Gresham House Asset Management	41,217,967	24.2%
Octopus Investments	25,005,466	14.7%
Rathbones	13,943,625	8.2%
Directors	8,702,609	5.1%
BGF	8,158,155	4.8%
Artemis Investment Management	6,568,965	3.9%
Liontrust Asset Management	6,291,230	3.7%
Directors
Henrik Bang	4,473,777	2.6%
James Ormondroyd	3,117,604	1.8%
Michael Jackson	941,450	0.6%
James Platt	145,279	0.1%
Richard Hughes	14,499	0.0%
Nigel Halkes	10,000	0.0%
Totals
Shares held by Directors	8,702,609	5.1%
Shares held by substantial shareholders	72,514,663	42.5%
Total shares not in public hands	81,217,272	47.6%
Shares in public hands	89,379,308	52.4%
Total shares in issue with voting rights	170,596,580	100.0%

Significant company shareholders